Date: July 23, 2025 | Time: 10:00 AM EDT | Format: Online | Free Registration
Creative Biolabs is honored to invite Dr. Francesc Guix to speak on the double-edged role of extracellular vesicles in Alzheimer's disease.
Key Points
EV Characteristics: How nano-sized, cell-released vesicles transport nucleic acids, proteins, etc. and facilitate cell-to-cell communication.
The Role of EVs in Brain Physiology: EVs support communication between neurons and glia, contributing to brain homeostasis.
The Dual Role of EVs in AD: EVs help clear toxic proteins but may also spread misfolded proteins (e.g., tau, A尾) and enhance neuroinflammation.
Therapeutic Potential: Primarily discussing the application of targeted EVs for AD treatment, enhanced beneficial effects, and application as diagnostic biomarkers.
About the Speaker
Assistant Professor of Neuroscience, IQS鈥揢niversitat Ramon Llull, Barcelona
* Research Focus on Alzheimer's Disease Pathology
Dr. Guix earned his degree in Human Biology from Universitat Pompeu Fabra and completed his Ph.D. under Prof. Francisco Jos茅 Mu帽oz, investigating how peroxynitrite contributes to neurofibrillary tangle formation. His findings were published in Brain, and an earlier review article of his has been widely cited.
* Postdoctoral Training under Established Neuroscientists
He conducted postdoctoral research with notable scientists including Kai Simons, Bart De Strooper, Dominic Walsh, and Dennis Selkoe. During this time, he contributed to studies on membrane microdomains, 纬-secretase biology, and protein homeostasis, publishing in journals such as EMBO Molecular Medicine. He is also a co-inventor on a patent related to tetraspanin-regulated protease activity.
* Research on Aging Neurons and Extracellular Vesicle Release
As a Marie Curie Fellow at the Centro de Biolog铆a Molecular 鈥淪evero Ochoa,鈥� Dr. Guix led work examining how aging neurons lose protein homeostasis and alter extracellular vesicle secretion, which forms the basis for his current research interests.
Creative Biolabs is honored to invite Dr. Francesc Guix to speak on the double-edged role of extracellular vesicles in Alzheimer's disease.
Key Points
EV Characteristics: How nano-sized, cell-released vesicles transport nucleic acids, proteins, etc. and facilitate cell-to-cell communication.
The Role of EVs in Brain Physiology: EVs support communication between neurons and glia, contributing to brain homeostasis.
The Dual Role of EVs in AD: EVs help clear toxic proteins but may also spread misfolded proteins (e.g., tau, A尾) and enhance neuroinflammation.
Therapeutic Potential: Primarily discussing the application of targeted EVs for AD treatment, enhanced beneficial effects, and application as diagnostic biomarkers.
About the Speaker
Assistant Professor of Neuroscience, IQS鈥揢niversitat Ramon Llull, Barcelona
* Research Focus on Alzheimer's Disease Pathology
Dr. Guix earned his degree in Human Biology from Universitat Pompeu Fabra and completed his Ph.D. under Prof. Francisco Jos茅 Mu帽oz, investigating how peroxynitrite contributes to neurofibrillary tangle formation. His findings were published in Brain, and an earlier review article of his has been widely cited.
* Postdoctoral Training under Established Neuroscientists
He conducted postdoctoral research with notable scientists including Kai Simons, Bart De Strooper, Dominic Walsh, and Dennis Selkoe. During this time, he contributed to studies on membrane microdomains, 纬-secretase biology, and protein homeostasis, publishing in journals such as EMBO Molecular Medicine. He is also a co-inventor on a patent related to tetraspanin-regulated protease activity.
* Research on Aging Neurons and Extracellular Vesicle Release
As a Marie Curie Fellow at the Centro de Biolog铆a Molecular 鈥淪evero Ochoa,鈥� Dr. Guix led work examining how aging neurons lose protein homeostasis and alter extracellular vesicle secretion, which forms the basis for his current research interests.
